Human AMH activation kit by CRISPRa

CAT#: GA100183

AMH CRISPRa kit - CRISPR gene activation of human anti-Mullerian hormone



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
AMH Capture Rabbit Monoclonal antibody,clone OTIR5D9
    • 100 ug

CNY 2,600.00
CNY 3,700.00


AMH (Myc-DDK-tagged)-Human anti-Mullerian hormone (AMH)
    • 10 ug

CNY 6,256.00


AMH biotinylated detection Rabbit Monoclonal antibody,clone OTIR5C11
    • 50 ug

CNY 2,700.00
CNY 3,980.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol AMH
Locus ID 268
Kit Components

GA100183G1, AMH gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100183G2, AMH gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100183G3, AMH gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000479
Synonyms MIF; MIS
Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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