Human Prostate Specific Antigen (KLK3) activation kit by CRISPRa

CAT#: GA100251

KLK3 CRISPRa kit - CRISPR gene activation of human kallikrein related peptidase 3



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
KLK3 (Myc-DDK-tagged)-Human kallikrein-related peptidase 3 (KLK3), transcript variant 1
    • 10 ug

CNY 2,400.00
CNY 3,705.00


KLK3 mouse monoclonal antibody, clone OTI1F7 (formerly 1F7)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


KLK3 mouse monoclonal antibody, clone OTI2C9 (formerly 2C9)
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol KLK3
Locus ID 354
Kit Components

GA100251G1, Prostate Specific Antigen gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100251G2, Prostate Specific Antigen gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100251G3, Prostate Specific Antigen gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001030047, NM_001030048, NM_001030049, NM_001030050, NM_001648, NM_145864
Synonyms APS; hK3; KLK2A1; PSA
Summary Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease which is synthesized in the epithelial cells of the prostate gland, and is present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. The serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Dec 2019]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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