Human Actin Regulatory Protein CAPG (CAPG) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CAPG
Locus ID	822
Kit Components	GA100575G1, Actin Regulatory Protein CAPG gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100575G2, Actin Regulatory Protein CAPG gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100575G3, Actin Regulatory Protein CAPG gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001256139, NM_001256140, NM_001320732, NM_001320733, NM_001320734, NM_001747
Synonyms	AFCP; HEL-S-66; MCP
Summary	This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012]

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