Human Caspase 3 (CASP3) activation kit by CRISPRa

CAT#: GA100589

CASP3 CRISPRa kit - CRISPR gene activation of human caspase 3



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Mouse Monoclonal Antibody against Caspase 3 (CPP32 4-1-18)
    • 200 ul

CNY 5,381.00


CASP3 (Myc-DDK-tagged)-Human caspase 3, apoptosis-related cysteine peptidase (CASP3), transcript variant alpha
    • 10 ug

CNY 2,400.00
CNY 3,990.00


CASP3 mouse monoclonal antibody,clone OTI1D2
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CASP3
Locus ID 836
Kit Components

GA100589G1, Caspase 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100589G2, Caspase 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100589G3, Caspase 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_004346, NM_032991, NM_001354777, NM_001354778, NM_001354779, NM_001354780, NM_001354781, NM_001354782, NM_001354783, NM_001354784
Synonyms CPP32; CPP32B; SCA-1
Summary The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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