Human CDH12 activation kit by CRISPRa

CAT#: GA100724

CDH12 CRISPRa kit - CRISPR gene activation of human cadherin 12



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
CDH12 rabbit polyclonal antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


CDH12 (Myc-DDK-tagged)-Human cadherin 12, type 2 (N-cadherin 2) (CDH12)
    • 10 ug

CNY 8,720.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CDH12
Locus ID 1010
Kit Components

GA100724G1, CDH12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100724G2, CDH12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100724G3, CDH12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001317227, NM_001317228, NM_004061, NM_001364105, NM_001364106, NM_001364109, NM_001364104, NM_001364107, NM_001364108
Synonyms CDHB
Summary This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. [provided by RefSeq, Nov 2015]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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