Human CISH activation kit by CRISPRa
CAT#: GA100828
CISH CRISPRa kit - CRISPR gene activation of human cytokine inducible SH2 containing protein
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | CISH |
Locus ID | 1154 |
Kit Components | GA100828G1, CISH gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100828G2, CISH gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100828G3, CISH gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_013324, NM_145071 |
Synonyms | BACTS2; CIS; CIS-1; G18; SOCS |
Summary | The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN406496 | CISH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |