Human Collagen VI (COL6A1) activation kit by CRISPRa

CAT#: GA100905

COL6A1 CRISPRa kit - CRISPR gene activation of human collagen type VI alpha 1 chain



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
COL6A1 mouse monoclonal antibody,clone OTI1G8
    • 100 ul

CNY 1,999.00
CNY 2,700.00


COL6A1 (Myc-DDK-tagged)-Human collagen, type VI, alpha 1 (COL6A1)
    • 10 ug

CNY 7,160.00


COL6A1 mouse monoclonal antibody,clone OTI1G8
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol COL6A1
Locus ID 1291
Kit Components

GA100905G1, Collagen VI gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100905G2, Collagen VI gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100905G3, Collagen VI gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001848
Synonyms BTHLM1; OPLL; UCHMD1
Summary The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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