Human DPP6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DPP6
Locus ID	1804
Kit Components	GA101257G1, DPP6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101257G2, DPP6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101257G3, DPP6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001039350, NM_001290252, NM_001290253, NM_001936, NM_130797, NM_001364497, NM_001364499, NM_001364500, NM_001364502, NM_001364498, NM_001364501, NR_157195, NR_157196
Synonyms	DPL1; DPPX; MRD33; VF2
Summary	This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

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