Human EGF activation kit by CRISPRa

CAT#: GA101349

EGF CRISPRa kit - CRISPR gene activation of human epidermal growth factor



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
EGF mouse monoclonal antibody,clone OTI2F9
    • 100 ul

CNY 1,999.00
CNY 2,700.00


EGF (Myc-DDK-tagged)-Human epidermal growth factor (EGF), transcript variant 1
    • 10 ug

CNY 8,408.00


EGF mouse monoclonal antibody,clone OTI8E2
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol EGF
Locus ID 1950
Kit Components

GA101349G1, EGF gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101349G2, EGF gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101349G3, EGF gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001178130, NM_001178131, NM_001963, NM_001357021
Synonyms HOMG4; URG
Summary This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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