Human EVI1 (MECOM) activation kit by CRISPRa

CAT#: GA101479

MECOM CRISPRa kit - CRISPR gene activation of human MDS1 and EVI1 complex locus



  See Other Versions

CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
MECOM rabbit polyclonal antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


MECOM (Myc-DDK-tagged)-Human MDS1 and EVI1 complex locus (MECOM), transcript variant 2
    • 10 ug

CNY 7,320.00


Rabbit Polyclonal EVI1 Antibody
    • 100 ug

CNY 5,302.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol MECOM
Locus ID 2122
Kit Components

GA101479G1, EVI1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101479G2, EVI1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101479G3, EVI1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001105077, NM_001105078, NM_001163999, NM_001164000, NM_001205194, NM_004991, NM_005241, NM_001366467, NM_001366469, NM_001366470, NM_001366471, NM_001366466, NM_001366468, NM_001366472, NM_001366473, NM_001366474
Synonyms AML1-EVI-1; EVI1; MDS1; MDS1-EVI1; PRDM3
Summary The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Other Versions

Customer Reviews 
Loading...