Human HARS1 activation kit by CRISPRa
CAT#: GA102065
HARS CRISPRa kit - CRISPR gene activation of human histidyl-tRNA synthetase
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | HARS1 |
Locus ID | 3035 |
Kit Components | GA102065G1, HARS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102065G2, HARS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102065G3, HARS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001258040, NM_001258041, NM_001258042, NM_001289092, NM_001289093, NM_001289094, NM_002109 |
Synonyms | CMT2W; HRS; USH3B |
Summary | Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN404009 | HARS - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |