Human Hemoglobin subunit delta (HBD) activation kit by CRISPRa
CAT#: GA102073
HBD CRISPRa kit - CRISPR gene activation of human hemoglobin subunit delta
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | HBD |
Locus ID | 3045 |
Kit Components | GA102073G1, Hemoglobin subunit delta gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102073G2, Hemoglobin subunit delta gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102073G3, Hemoglobin subunit delta gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_000519 |
Synonyms | delta-globin chain; delta globin; hemoglobin, delta; OTTHUMP00000069639 |
Summary | The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia. [provided by RefSeq, Jul 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN409999 | HBD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |