Human HMGCS1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HMGCS1
Locus ID	3157
Kit Components	GA102152G1, HMGCS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102152G2, HMGCS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102152G3, HMGCS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001098272, NM_001324219, NM_001324220, NM_001324222, NM_001324223, NM_001324224, NM_001330663, NM_002130, NM_001364188
Synonyms	HMGCS
Summary	This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.[UniProtKB/Swiss-Prot Function]

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