Human 5 HT1F (HTR1F) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HTR1F
Locus ID	3355
Kit Components	GA102283G1, 5 HT1F gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102283G2, 5 HT1F gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102283G3, 5 HT1F gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000866, NM_001322208, NM_001322209, NM_001322210
Synonyms	5-HT-1F; 5-HT1F; 5HT6; HTR1EL; MR77
Summary	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.[UniProtKB/Swiss-Prot Function]

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