Human IL2 Receptor gamma (IL2RG) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IL2RG
Locus ID	3561
Kit Components	GA102379G1, IL2 Receptor gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102379G2, IL2 Receptor gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102379G3, IL2 Receptor gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000206
Synonyms	CD132; CIDX; IL-2RG; IMD4; P64; SCIDX; SCIDX1
Summary	The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010]

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