Human Integrin Linked Kinase (ILK) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ILK
Locus ID	3611
Kit Components	GA102417G1, Integrin Linked Kinase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102417G2, Integrin Linked Kinase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102417G3, Integrin Linked Kinase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001014794, NM_001014795, NM_001278441, NM_001278442, NM_004517
Synonyms	HEL-S-28; ILK-1; ILK-2; P59; p59ILK
Summary	This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

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