Human Lamin B1 (LMNB1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LMNB1
Locus ID	4001
Kit Components	GA102712G1, Lamin B1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102712G2, Lamin B1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102712G3, Lamin B1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001198557, NM_005573, NR_134488
Synonyms	ADLD; LMN; LMN2; LMNB
Summary	This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

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