Human LOX activation kit by CRISPRa

CAT#: GA102722

LOX CRISPRa kit - CRISPR gene activation of human lysyl oxidase



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
LOX mouse monoclonal antibody, clone OTI9G2 (formerly 9G2)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


LOX (Myc-DDK-tagged)-Human lysyl oxidase (LOX), transcript variant 1
    • 10 ug

CNY 5,488.00


LOX biotinylated mouse monoclonal detection antibody, validated for ELISA and Luminex assays
    • 50 ug

CNY 2,700.00
CNY 3,790.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol LOX
Locus ID 4015
Kit Components

GA102722G1, LOX gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102722G2, LOX gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102722G3, LOX gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001178102, NM_001317073, NM_002317
Synonyms MGC105112
Summary This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections. [provided by RefSeq, Jul 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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