Human MGAT1 activation kit by CRISPRa

CAT#: GA102892

MGAT1 CRISPRa kit - CRISPR gene activation of human mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

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MGAT1 Rabbit polyclonal Antibody
    • 100 ul

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MGAT1 (Myc-DDK-tagged)-Human mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (MGAT1), transcript variant 2
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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol MGAT1
Locus ID 4245
Kit Components

GA102892G1, MGAT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102892G2, MGAT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102892G3, MGAT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001114617, NM_001114618, NM_001114619, NM_001114620, NM_002406, NM_001364390, NR_157150, NR_157151, NM_001364379, NM_001364380, NM_001364384, NM_001364386, NM_001364388, NM_001364391, NM_001364392, NM_001364393, NM_001364394, NM_001364377, NM_001364381, NM_001364382, NM_001364383, NM_001364385, NM_001364387, NM_001364389, NM_001364395, NR_157152, NR_157153, NR_157154
Synonyms GLCNAC-TI; GLCT1; GLYT1; GNT-1; GNT-I; MGAT
Summary There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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