Human Mannose Phosphate Isomerase (MPI) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MPI
Locus ID	4351
Kit Components	GA102961G1, Mannose Phosphate Isomerase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102961G2, Mannose Phosphate Isomerase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102961G3, Mannose Phosphate Isomerase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001289155, NM_001289156, NM_001289157, NM_002435, NM_001330372
Synonyms	CDG1B; PMI; PMI1
Summary	Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

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