Human Nkx3.1 (NKX3-1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NKX3-1
Locus ID	4824
Kit Components	GA103217G1, Nkx3.1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103217G2, Nkx3.1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103217G3, Nkx3.1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001256339, NM_006167, NR_046072
Synonyms	BAPX2; NKX3; NKX3.1; NKX3A
Summary	This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jan 2012]

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