Human NME3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NME3
Locus ID	4832
Kit Components	GA103224G1, NME3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103224G2, NME3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103224G3, NME3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_002513
Synonyms	c371H6.2; DR-nm23; NDPK-C; NDPKC; NM23-H3; NM23H3
Summary	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.[UniProtKB/Swiss-Prot Function]

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