Human TrkB (NTRK2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NTRK2
Locus ID	4915
Kit Components	GA103282G1, TrkB gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103282G2, TrkB gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103282G3, TrkB gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001007097, NM_001018064, NM_001018065, NM_001018066, NM_001291937, NM_006180, NM_001369532, NM_001369533, NM_001369534, NM_001369535, NM_001369538, NM_001369539, NM_001369540, NM_001369546, NM_001369549, NM_001369550, NM_001369552, NM_001369536, NM_001369537, NM_001369541, NM_001369542, NM_001369543, NM_001369544, NM_001369545, NM_001369547, NM_001369548, NM_001369551
Synonyms	GP145-TrkB; trk-B; TRKB
Summary	This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.