Human PDE1A activation kit by CRISPRa

CAT#: GA103433

PDE1A CRISPRa kit - CRISPR gene activation of human phosphodiesterase 1A



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
PDE1A mouse monoclonal antibody, clone OTI7D5 (formerly 7D5)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


PDE1A (Myc-DDK-tagged)-Human phosphodiesterase 1A, calmodulin-dependent (PDE1A), transcript variant 1
    • 10 ug

CNY 4,056.00


PDE1A mouse monoclonal antibody, clone OTI5H4 (formerly 5H4)
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PDE1A
Locus ID 5136
Kit Components

GA103433G1, PDE1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103433G2, PDE1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103433G3, PDE1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001003683, NM_001258312, NM_001258313, NM_001258314, NM_005019, NM_001363871
Synonyms CAM-PDE-1A; HCAM-1; HCAM1; HSPDE1A
Summary Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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