Human PDE3A activation kit by CRISPRa
CAT#: GA103436
PDE3A CRISPRa kit - CRISPR gene activation of human phosphodiesterase 3A
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | PDE3A |
Locus ID | 5139 |
Kit Components | GA103436G1, PDE3A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103436G2, PDE3A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103436G3, PDE3A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_000921, NM_001244683 |
Synonyms | CGI-PDE; CGI-PDE-A; CGI-PDE A |
Summary | This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN422006 | PDE3A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |