Human Pyruvate Kinase (PKLR) activation kit by CRISPRa

CAT#: GA103574

PKLR CRISPRa kit - CRISPR gene activation of human pyruvate kinase L/R



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
PKLR mouse monoclonal antibody, clone OTI1H4 (formerly 1H4)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


PKLR (Myc-DDK-tagged)-Human pyruvate kinase, liver and RBC (PKLR), nuclear gene encoding mitochondrial protein, transcript variant 1
    • 10 ug

CNY 4,272.00


PKLR mouse monoclonal antibody, clone OTI1C7 (formerly 1C7)
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PKLR
Locus ID 5313
Kit Components

GA103574G1, Pyruvate Kinase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103574G2, Pyruvate Kinase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103574G3, Pyruvate Kinase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000298, NM_181871
Synonyms PK1; PKL; PKR; PKRL; RPK
Summary The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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