Human Phospholipase A2 (PLA2G4A) activation kit by CRISPRa

CAT#: GA103582

PLA2G4A CRISPRa kit - CRISPR gene activation of human phospholipase A2 group IVA



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit Polyclonal Anti-PLA2G4A Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


PLA2G4A (Myc-DDK-tagged)-Human phospholipase A2, group IVA (cytosolic, calcium-dependent) (PLA2G4A)
    • 10 ug

CNY 8,232.00


Phospho-PLA2G4A-S505 Rabbit polyclonal Antibody
    • 100 ul

CNY 2,900.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PLA2G4A
Locus ID 5321
Kit Components

GA103582G1, Phospholipase A2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103582G2, Phospholipase A2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103582G3, Phospholipase A2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001311193, NM_024420
Synonyms cPLA2; cPLA2-alpha; PLA2G4
Summary This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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