Human Phosphoribosyl pyrophosphate amidotransferase (PPAT) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PPAT
Locus ID	5471
Kit Components	GA103691G1, Phosphoribosyl pyrophosphate amidotransferase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103691G2, Phosphoribosyl pyrophosphate amidotransferase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103691G3, Phosphoribosyl pyrophosphate amidotransferase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_002703, NR_156493
Synonyms	ATASE; GPAT; PRAT
Summary	The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. [provided by RefSeq, Mar 2011]

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