Human Retinoid X Receptor gamma (RXRG) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RXRG
Locus ID	6258
Kit Components	GA104241G1, Retinoid X Receptor gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104241G2, Retinoid X Receptor gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104241G3, Retinoid X Receptor gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001009598, NM_001256570, NM_001256571, NM_006917, NR_033824
Synonyms	NR2B3; RXRC
Summary	This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]

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