Human SERPINB3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SERPINB3
Locus ID	6317
Kit Components	GA104285G1, SERPINB3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104285G2, SERPINB3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104285G3, SERPINB3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_006919
Synonyms	HsT1196; SCC; SCCA-1; SCCA-PD; SCCA1; SSCA1; T4-A
Summary	May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).[UniProtKB/Swiss-Prot Function]

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