Human Syndecan 1 (SDC1) activation kit by CRISPRa

CAT#: GA104338

SDC1 CRISPRa kit - CRISPR gene activation of human syndecan 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
SDC1 mouse monoclonal antibody, clone OTI3G1
    • 100 ul

CNY 1,999.00
CNY 3,600.00


SDC1 (Myc-DDK-tagged)-Human syndecan 1 (SDC1), transcript variant 1
    • 10 ug

CNY 3,600.00
CNY 4,940.00


SDC1 Rabbit Polyclonal Antibody
    • 30 ul

CNY 870.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol SDC1
Locus ID 6382
Kit Components

GA104338G1, Syndecan 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104338G2, Syndecan 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104338G3, Syndecan 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001006946, NM_002997
Synonyms CD138; SDC; SYND1; syndecan
Summary The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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