Human SETMAR activation kit by CRISPRa
CAT#: GA104365
SETMAR CRISPRa kit - CRISPR gene activation of human SET domain and mariner transposase fusion gene
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | SETMAR |
Locus ID | 6419 |
Kit Components | GA104365G1, SETMAR gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104365G2, SETMAR gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104365G3, SETMAR gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001243723, NM_001276325, NM_001320676, NM_001320677, NM_001320678, NM_006515, NR_024022, NR_075073 |
Synonyms | Mar1; METNASE |
Summary | This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN422705 | SETMAR - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |