Human beta 1 Spectrin (SPTB) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SPTB
Locus ID	6710
Kit Components	GA104609G1, beta 1 Spectrin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104609G2, beta 1 Spectrin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104609G3, beta 1 Spectrin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000347, NM_001024858, NM_001355436, NM_001355437
Synonyms	EL3; HS2; HSPTB1; SPH2
Summary	This locus encodes a member of the spectrin gene family. Spectrin proteins, along with ankyrin, play a role in cell membrane organization and stability. The protein encoded by this locus functions in stability of erythrocyte membranes, and mutations in this gene have been associated with spherocytosis type 2, hereditary elliptocytosis, and neonatal hemolytic anemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]

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