Human TAF10 activation kit by CRISPRa

CAT#: GA104740

TAF10 CRISPRa kit - CRISPR gene activation of human TATA-box binding protein associated factor 10



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
Rabbit Polyclonal Anti-TAF10 Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TAF10 (Myc-DDK-tagged)-Human TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa (TAF10)
    • 10 ug

CNY 2,400.00
CNY 3,705.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol TAF10
Locus ID 6881
Kit Components

GA104740G1, TAF10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104740G2, TAF10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104740G3, TAF10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_006284
Synonyms TAF2A; TAF2H; TAFII30
Summary Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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