Human TBXAS1 activation kit by CRISPRa

CAT#: GA104771

TBXAS1 CRISPRa kit - CRISPR gene activation of human thromboxane A synthase 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Anti-TBXAS1 (Thromboxane synthase) mouse monoclonal antibody, clone OTI2C1 (formerly 2C1)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TBXAS1 (Myc-DDK-tagged)-Human thromboxane A synthase 1 (platelet) (TBXAS1), transcript variant 1
    • 10 ug

CNY 3,976.00
CNY 3,990.00


TBXAS biotinylated mouse monoclonal detection antibody, validated for Luminex assays
    • 50 ug

CNY 2,700.00
CNY 3,790.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol TBXAS1
Locus ID 6916
Kit Components

GA104771G1, TBXAS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104771G2, TBXAS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104771G3, TBXAS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001061, NM_001130966, NM_001166253, NM_001166254, NM_001314028, NM_030984, NR_029394, NM_001366538, NR_159363, NR_159365, NM_001366537, NR_159364
Synonyms BDPLT14; CYP5; CYP5A1; GHOSAL; THAS; TS; TXAS; TXS
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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