Human VRK2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	VRK2
Locus ID	7444
Kit Components	GA105131G1, VRK2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105131G2, VRK2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105131G3, VRK2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001130480, NM_001130481, NM_001130482, NM_001130483, NM_001136027, NM_001288836, NM_001288837, NM_001288838, NM_001288839, NM_006296, NR_036441, NR_049781
Synonyms	vaccinia-related kinase-2; vaccinia related kinase 2; vaccinia virus B1R-related kinase 2
Summary	This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity. [provided by RefSeq, Jan 2014]

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