Human CILP activation kit by CRISPRa

CAT#: GA105606

CILP CRISPRa kit - CRISPR gene activation of human cartilage intermediate layer protein



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Goat Polyclonal Antibody against CILP
    • 100 ug

CNY 5,371.00


CILP (Myc-DDK-tagged)-Human cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (CILP)
    • 10 ug

CNY 12,368.00


CILP Antibody - C-terminal region
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CILP
Locus ID 8483
Kit Components

GA105606G1, CILP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105606G2, CILP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105606G3, CILP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_003613
Synonyms CILP-1; HsT18872
Summary Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease. [provided by RefSeq, Sep 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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