Human DPM2 activation kit by CRISPRa

CAT#: GA105862

DPM2 CRISPRa kit - CRISPR gene activation of human dolichyl-phosphate mannosyltransferase subunit 2, regulatory



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
DPM2 Antibody - middle region
    • 100 ul

CNY 5,250.00


DPM2 (Myc-DDK-tagged)-Human dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit (DPM2)
    • 10 ug

CNY 1,200.00
CNY 3,705.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol DPM2
Locus ID 8818
Kit Components

GA105862G1, DPM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105862G2, DPM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105862G3, DPM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_003863, NM_152690
Synonyms CDG1U
Summary Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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