Human ST3GAL5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ST3GAL5
Locus ID	8869
Kit Components	GA105903G1, ST3GAL5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105903G2, ST3GAL5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105903G3, ST3GAL5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001042437, NM_003896, NM_001354223, NM_001354224, NM_001354226, NM_001354227, NM_001354229, NM_001354233, NM_001354234, NM_001354238, NM_001354247, NM_001354248, NM_001363847
Synonyms	SATI; SIAT9; SIATGM3S; SPDRS; ST3GalV
Summary	Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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