Human PRPF4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PRPF4
Locus ID	9128
Kit Components	GA106081G1, PRPF4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106081G2, PRPF4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106081G3, PRPF4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001244926, NM_004697, NM_001322266, NM_001322267, NR_136265, NR_136266
Synonyms	HPRP4; HPRP4P; PRP4; Prp4p; RP70; SNRNP60
Summary	The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]

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