Human GPR56 (ADGRG1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ADGRG1
Locus ID	9289
Kit Components	GA106194G1, GPR56 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106194G2, GPR56 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106194G3, GPR56 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001145770, NM_001145771, NM_001145772, NM_001145773, NM_001145774, NM_001290142, NM_001290143, NM_001290144, NM_005682, NM_201524, NM_201525, NM_001370428, NM_001370429, NM_001370430, NM_001370432, NM_001370433, NM_001370434, NM_001370436, NM_001370439, NM_001370440, NM_001370451, NM_001370431, NM_001370435, NM_001370437, NM_001370438, NM_001370441, NM_001370442, NM_001370453, NM_001370454
Synonyms	BFPP; BPPR; GPR56; TM7LN4; TM7XN1
Summary	This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

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