Human SLC4A7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SLC4A7
Locus ID	9497
Kit Components	GA106347G1, SLC4A7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106347G2, SLC4A7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106347G3, SLC4A7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001258379, NM_001258380, NM_003615, NM_001321103, NM_001321104, NM_001321105, NM_001321106, NM_001321107, NM_001321108, NR_135541, NR_135542, NR_135543, NR_135544
Synonyms	NBC2; NBC3; NBCN1; SBC2; SLC4A6
Summary	This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]

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