Human GAL3ST1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GAL3ST1
Locus ID	9514
Kit Components	GA106360G1, GAL3ST1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106360G2, GAL3ST1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106360G3, GAL3ST1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001318103, NM_001318104, NM_001318105, NM_001318106, NM_001318107, NM_001318108, NM_001318109, NM_001318110, NM_001318111, NM_001318112, NM_001318113, NM_001318114, NM_001318115, NM_001318116, NM_004861
Synonyms	CST
Summary	Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. This gene encodes galactosylceramide sulfotransferase, which catalyzes the sulfation of membrane glycolipids including the final step in the synthesis of sulfatide, a major lipid component of the myelin sheath. This gene exhibits elevated expression in ovarian epithelial carcinoma and the encoded enzyme exhibits elevated activity in renal cell carcinoma. Mutations in this gene may be associated with reduced insulin resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

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