Human NCoR (NCOR1) activation kit by CRISPRa
CAT#: GA106435
NCOR1 CRISPRa kit - CRISPR gene activation of human nuclear receptor corepressor 1
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | NCOR1 |
Locus ID | 9611 |
Kit Components | GA106435G1, NCoR gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106435G2, NCoR gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106435G3, NCoR gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001190438, NM_001190440, NM_006311 |
Synonyms | hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1 |
Summary | This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010] |
Documents
Resources
基因表达相关资源 |
Other Versions
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KN213467 | NCOR1 - human gene knockout kit via CRISPR, HDR mediated |
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KN213467BN | NCOR1 - human gene knockout kit via CRISPR, HDR mediated |
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KN213467LP | NCOR1 - human gene knockout kit via CRISPR, HDR mediated |
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KN213467RB | NCOR1 - human gene knockout kit via CRISPR, HDR mediated |
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KN413467 | NCOR1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
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