Human NCoR (NCOR1) activation kit by CRISPRa

CAT#: GA106435

NCOR1 CRISPRa kit - CRISPR gene activation of human nuclear receptor corepressor 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
NCOR1 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


NCOR1 (Myc-DDK-tagged)-Human nuclear receptor corepressor 1 (NCOR1), transcript variant 1
    • 10 ug

CNY 16,104.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol NCOR1
Locus ID 9611
Kit Components

GA106435G1, NCoR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106435G2, NCoR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106435G3, NCoR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001190438, NM_001190440, NM_006311
Synonyms hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1
Summary This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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