Human MICAL2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MICAL2
Locus ID	9645
Kit Components	GA106462G1, MICAL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106462G2, MICAL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106462G3, MICAL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001282663, NM_001282664, NM_001282665, NM_001282666, NM_001282667, NM_001282668, NM_014632, NM_001346292, NM_001346293, NM_001346294, NM_001346295, NM_001346296, NM_001346297, NM_001346298, NM_001346299, NR_144415, NR_144416, NR_144417, NR_144418, NR_144419, NR_144420
Synonyms	MICAL-2; MICAL2PV1; MICAL2PV2
Summary	The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]

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