Human LNK (SH2B3) activation kit by CRISPRa

CAT#: GA106787

SH2B3 CRISPRa kit - CRISPR gene activation of human SH2B adaptor protein 3



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
SH2B3 (LNK) mouse monoclonal antibody, clone OTI2D8 (formerly 2D8)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


SH2B3 (Myc-DDK-tagged)-Human SH2B adaptor protein 3 (SH2B3)
    • 10 ug

CNY 4,280.00
CNY 4,560.00


SH2B3 (LNK) mouse monoclonal antibody, clone OTI1F6 (formerly 1F6)
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol SH2B3
Locus ID 10019
Kit Components

GA106787G1, LNK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106787G2, LNK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106787G3, LNK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001291424, NM_005475
Synonyms IDDM20; LNK
Summary This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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