Human TNIP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TNIP1
Locus ID	10318
Kit Components	GA107031G1, TNIP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107031G2, TNIP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107031G3, TNIP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001252385, NM_001252386, NM_001252390, NM_001252391, NM_001252392, NM_001252393, NM_001258454, NM_001258455, NM_001258456, NM_006058, NM_001364486, NM_001364487
Synonyms	ABIN-1; NAF1; nip40-1; VAN
Summary	This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

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