Human SPON2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SPON2
Locus ID	10417
Kit Components	GA107100G1, SPON2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107100G2, SPON2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107100G3, SPON2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001128325, NM_001199021, NM_012445
Synonyms	DIL-1; DIL1; M-SPONDIN; MINDIN
Summary	Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens (By similarity). Binds bacterial lipopolysaccharide (LPS).[UniProtKB/Swiss-Prot Function]

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