Human ARIH2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARIH2
Locus ID	10425
Kit Components	GA107108G1, ARIH2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107108G2, ARIH2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107108G3, ARIH2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001317333, NM_001317334, NM_006321, NM_001349209, NM_001349210, NM_001349211, NM_001349212, NM_001349213, NM_001349214, NM_001349215, NM_001349216, NM_001349217, NM_001349218, NM_001349219, NM_001349220, NM_001349221, NM_001349222, NM_001349223, NM_001349224, NM_001349225, NM_001349226, NM_001349227, NM_001349228, NM_001349229, NM_001349230, NR_146082, NR_146083, NR_146084, NR_146085
Synonyms	ARI2; TRIAD1
Summary	The protein encoded by this gene is an E3 ubiquitin-protein ligase that polyubiquitinates some proteins, tagging them for degradation. The encoded protein upregulates p53 in some cancer cells and may inhibit myelopoiesis. Several transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been determined yet. [provided by RefSeq, Nov 2015]

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