Human SMC2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SMC2
Locus ID	10592
Kit Components	GA107249G1, SMC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107249G2, SMC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107249G3, SMC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001042550, NM_001042551, NM_001265602, NM_006444
Synonyms	CAP-E; CAPE; SMC-2; SMC2L1
Summary	Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.[UniProtKB/Swiss-Prot Function]

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